{"id":11163,"date":"2025-12-24T15:14:16","date_gmt":"2025-12-24T13:14:16","guid":{"rendered":"https:\/\/medilab.km.ua\/?p=11163"},"modified":"2026-04-20T18:53:29","modified_gmt":"2026-04-20T15:53:29","slug":"what-is-mass-spectrometry-and-why-is-it-considered-one-of-the-most-accurate-in-medicine","status":"publish","type":"post","link":"https:\/\/medilab.km.ua\/en\/what-is-mass-spectrometry-and-why-is-it-considered-one-of-the-most-accurate-in-medicine\/","title":{"rendered":"Mass spectrometry: what is this method and why is it considered one of the most accurate in medicine"},"content":{"rendered":"
\n \n
\n \n
\n
\n \n\n
<\/div>\n <\/div>\n
\n \n\n
<\/div>\n <\/div>\n
\n \n\n
<\/div>\n <\/div>\n
\n \n\n
<\/div>\n <\/div>\n
\n \n\n
<\/div>\n <\/div>\n <\/div>\n \n
\n
\n \n\n
<\/div>\n <\/div>\n
\n \n\n
<\/div>\n <\/div>\n
\n \n\n
<\/div>\n <\/div>\n
\n \n\n
<\/div>\n <\/div>\n
\n \n\n
<\/div>\n <\/div>\n <\/div>\n<\/div>\n \n\n
\n 4.8\/5 - (170 votes) <\/div>\n <\/div>\n

Mass spectrometry is a highly accurate laboratory diagnostic method that allows you to determine the composition of biological samples at the molecular level. It is used when conventional analyses do not give a sufficiently accurate answer or when it is important to detect substances in extremely low concentrations. In modern medicine, mass spectrometry is used for the diagnosis of hormonal disorders, drug control, toxicological studies, and screening for rare diseases.<\/p>\n

The method is considered one of the most reliable in laboratory practice, as it allows for the identification of specific molecules, not just an estimate of their approximate concentration.<\/p>\n

How mass spectrometry works in simple words<\/h3>\n

The essence of mass spectrometry is to measure the mass of molecules. During analysis, the sample is first converted into charged particles - ions. These ions are then separated depending on their mass and charge. The result is a mass spectrum - a unique set of signals that allows you to accurately determine which substances are present in the sample and in what quantity.<\/p>\n

In medical laboratories, a combination of liquid chromatography and mass spectrometry (LC-MS or LC-MS\/MS) is most often used. This approach increases the accuracy of the analysis and reduces the risk of errors, especially when the composition of biological fluids is complex.<\/p>\n

In what cases is mass spectrometry used?<\/h3>\n

Mass spectrometry studies are not prescribed to all patients in a row, but only when maximum accuracy or detail of the results is required.<\/p>\n

The most common areas of application:<\/p>\n