{"id":11413,"date":"2026-02-09T15:13:21","date_gmt":"2026-02-09T13:13:21","guid":{"rendered":"https:\/\/medilab.km.ua\/?p=11413"},"modified":"2026-04-20T18:53:25","modified_gmt":"2026-04-20T15:53:25","slug":"test-for-which-chancre-is-present-diagnosis-of-chancre-symptoms-and-examination-algorithm","status":"publish","type":"post","link":"https:\/\/medilab.km.ua\/en\/test-for-which-chancre-is-present-diagnosis-of-chancre-symptoms-and-examination-algorithm\/","title":{"rendered":"Soft chancre test: modern chancroid diagnostics, symptoms and examination algorithm"},"content":{"rendered":"<p data-start=\"90\" data-end=\"490\">The chancroid test is a laboratory test to confirm chancroid, a sexually transmitted bacterial infection that causes painful sores on the genitals. The causative agent is <em data-start=\"294\" data-end=\"315\">Haemophilus ducreyi<\/em>. Despite the relatively low prevalence in some regions, timely diagnosis is crucial: ulcerative lesions increase the risk of transmission of other STIs, including HIV.<\/p>\n<p data-start=\"492\" data-end=\"655\">This article contains practical information: when a test for soft chancre is needed, which tests are informative, how to prepare, and why differential diagnosis is important.<\/p>\n<h2 data-start=\"657\" data-end=\"717\">What is a soft chancre and why is laboratory testing important?<\/h2>\n<p data-start=\"719\" data-end=\"1012\">Chancroid is an infection that causes painful ulcers with soft, jagged edges and possible involvement of the inguinal lymph nodes. The clinical manifestations may resemble other <a href=\"https:\/\/medilab.km.ua\/en\/ipssh-analyses-diagnostics-of-infections-transmitted-sexually\/\">STIs<\/a>, so just looking at it is not enough. A soft chancre test is needed to confirm the bacterial nature of the process.<\/p>\n<p data-start=\"1014\" data-end=\"1166\">According to <span class=\"hover:entity-accent entity-underline inline cursor-pointer align-baseline\"><span class=\"whitespace-normal\">World Health Organization<\/span><\/span>, in regions with a high prevalence of STIs, chancroid remains a pressing public health problem.<\/p>\n<h2 data-start=\"1168\" data-end=\"1195\">Who is the examination indicated for?<\/h2>\n<p data-start=\"1197\" data-end=\"1230\">Testing is recommended if there is:<\/p>\n<ul data-start=\"1232\" data-end=\"1440\">\n<li data-start=\"1232\" data-end=\"1271\">\n<p data-start=\"1234\" data-end=\"1271\">painful sores on the genitals<\/p>\n<\/li>\n<li data-start=\"1272\" data-end=\"1314\">\n<p data-start=\"1274\" data-end=\"1314\">enlarged and painful inguinal lymph nodes<\/p>\n<\/li>\n<li data-start=\"1315\" data-end=\"1349\">\n<p data-start=\"1317\" data-end=\"1349\">suppuration of the lymph nodes (buboes)<\/p>\n<\/li>\n<li data-start=\"1350\" data-end=\"1391\">\n<p data-start=\"1352\" data-end=\"1391\">recent unprotected sexual intercourse<\/p>\n<\/li>\n<li data-start=\"1392\" data-end=\"1440\">\n<p data-start=\"1394\" data-end=\"1440\">symptoms not explained by other causes<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1442\" data-end=\"1539\">It is important not to delay the examination, as early confirmation allows you to quickly begin treatment.<\/p>\n<p data-start=\"1442\" data-end=\"1539\"><img decoding=\"async\" class=\"alignnone size-full wp-image-11415\" src=\"https:\/\/medilab.km.ua\/wp-content\/uploads\/2026\/02\/qC3a473VWp60DZ4froLS.jpg\" alt=\"Symptoms of soft chancre painful ulcers\" width=\"854\" height=\"520\" srcset=\"https:\/\/medilab.km.ua\/wp-content\/uploads\/2026\/02\/qC3a473VWp60DZ4froLS.jpg 854w, https:\/\/medilab.km.ua\/wp-content\/uploads\/2026\/02\/qC3a473VWp60DZ4froLS-300x183.jpg 300w, https:\/\/medilab.km.ua\/wp-content\/uploads\/2026\/02\/qC3a473VWp60DZ4froLS-768x468.jpg 768w, https:\/\/medilab.km.ua\/wp-content\/uploads\/2026\/02\/qC3a473VWp60DZ4froLS-18x12.jpg 18w, https:\/\/medilab.km.ua\/wp-content\/uploads\/2026\/02\/qC3a473VWp60DZ4froLS-600x365.jpg 600w, https:\/\/medilab.km.ua\/wp-content\/uploads\/2026\/02\/qC3a473VWp60DZ4froLS-150x91.jpg 150w\" sizes=\"(max-width: 854px) 100vw, 854px\" \/><\/p>\n<h2 data-start=\"1541\" data-end=\"1586\">What tests are included in the test for soft chancre?<\/h2>\n<p data-start=\"1588\" data-end=\"1671\">Diagnosis is usually complex, as other causes of ulcers must be ruled out.<\/p>\n<p data-start=\"1673\" data-end=\"1688\">Main methods:<\/p>\n<ul data-start=\"1690\" data-end=\"1886\">\n<li data-start=\"1690\" data-end=\"1772\">\n<p data-start=\"1692\" data-end=\"1772\">PCR on <em data-start=\"1699\" data-end=\"1720\">Haemophilus ducreyi<\/em> \u2014 the most sensitive method for detecting pathogen DNA<\/p>\n<\/li>\n<li data-start=\"1773\" data-end=\"1810\">\n<p data-start=\"1775\" data-end=\"1810\">bacteriological culture from the ulcer<\/p>\n<\/li>\n<li data-start=\"1811\" data-end=\"1832\">\n<p data-start=\"1813\" data-end=\"1832\">smear microscopy<\/p>\n<\/li>\n<li data-start=\"1833\" data-end=\"1886\">\n<p data-start=\"1835\" data-end=\"1886\">parallel tests for syphilis and <a class=\"wpil_keyword_link\" href=\"https:\/\/medilab.km.ua\/en\/genital-herpes-is-a-virus-that-needs-to-be-known-for-its-ability-to-live-in-the-body\/\"   title=\"Genital herpes: what you need to know about the virus that lives nearby\" data-wpil-keyword-link=\"linked\"  data-wpil-monitor-id=\"72\">genital herpes<\/a><\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1888\" data-end=\"2060\">Specialists <span class=\"hover:entity-accent entity-underline inline cursor-pointer align-baseline\"><span class=\"whitespace-normal\">Mayo Clinic<\/span><\/span> emphasize: in case of ulcerative lesions, differential diagnosis is mandatory, because the clinical picture may overlap.<\/p>\n<h2 data-start=\"2062\" data-end=\"2102\">Comparison: soft chancre or other STI<\/h2>\n<div class=\"TyagGW_tableContainer\">\n<div class=\"group TyagGW_tableWrapper flex flex-col-reverse w-fit\">\n<table class=\"w-fit min-w-(--thread-content-width)\" data-start=\"2104\" data-end=\"2451\">\n<thead data-start=\"2104\" data-end=\"2162\">\n<tr data-start=\"2104\" data-end=\"2162\">\n<th class=\"\" data-start=\"2104\" data-end=\"2115\" data-col-size=\"sm\">Criterion<\/th>\n<th class=\"\" data-start=\"2115\" data-end=\"2130\" data-col-size=\"sm\">Soft chancre<\/th>\n<th class=\"\" data-start=\"2130\" data-end=\"2140\" data-col-size=\"sm\">Syphilis<\/th>\n<th class=\"\" data-start=\"2140\" data-end=\"2162\" data-col-size=\"sm\">Genital herpes<\/th>\n<\/tr>\n<\/thead>\n<tbody data-start=\"2181\" data-end=\"2451\">\n<tr data-start=\"2181\" data-end=\"2242\">\n<td data-start=\"2181\" data-end=\"2193\" data-col-size=\"sm\">Soreness<\/td>\n<td data-start=\"2193\" data-end=\"2204\" data-col-size=\"sm\">Expressed<\/td>\n<td data-start=\"2204\" data-end=\"2224\" data-col-size=\"sm\">Usually absent<\/td>\n<td data-start=\"2224\" data-end=\"2242\" data-col-size=\"sm\">Painful blisters<\/td>\n<\/tr>\n<tr data-start=\"2243\" data-end=\"2312\">\n<td data-start=\"2243\" data-end=\"2258\" data-col-size=\"sm\">Ulcer edges<\/td>\n<td data-start=\"2258\" data-end=\"2275\" data-col-size=\"sm\">Uneven, soft<\/td>\n<td data-start=\"2275\" data-end=\"2291\" data-col-size=\"sm\">Dense, clear<\/td>\n<td data-start=\"2291\" data-end=\"2312\" data-col-size=\"sm\">Surface erosions<\/td>\n<\/tr>\n<tr data-start=\"2313\" data-end=\"2403\">\n<td data-start=\"2313\" data-end=\"2326\" data-col-size=\"sm\">Lymph nodes<\/td>\n<td data-start=\"2326\" data-end=\"2357\" data-col-size=\"sm\">Painful, may fester<\/td>\n<td data-start=\"2357\" data-end=\"2378\" data-col-size=\"sm\">More often painless<\/td>\n<td data-start=\"2378\" data-end=\"2403\" data-col-size=\"sm\">Can be increased<\/td>\n<\/tr>\n<tr data-start=\"2404\" data-end=\"2451\">\n<td data-start=\"2404\" data-end=\"2420\" data-col-size=\"sm\">Confirmation<\/td>\n<td data-start=\"2420\" data-end=\"2432\" data-col-size=\"sm\">PCR\/culture<\/td>\n<td data-start=\"2432\" data-end=\"2444\" data-col-size=\"sm\">Serology<\/td>\n<td data-start=\"2444\" data-end=\"2451\" data-col-size=\"sm\">PCR<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<p data-start=\"2453\" data-end=\"2566\">This table demonstrates why self-assessment of symptoms is unreliable\u2014a laboratory test for soft chancre is needed.<\/p>\n<h2 data-start=\"2568\" data-end=\"2604\">How to prepare for the analysis<\/h2>\n<p data-start=\"2606\" data-end=\"2641\">To increase the accuracy of the results:<\/p>\n<ul data-start=\"2643\" data-end=\"2851\">\n<li data-start=\"2643\" data-end=\"2696\">\n<p data-start=\"2645\" data-end=\"2696\">do not treat ulcers with antiseptics before the visit<\/p>\n<\/li>\n<li data-start=\"2697\" data-end=\"2745\">\n<p data-start=\"2699\" data-end=\"2745\">do not start antibiotics before specimen collection<\/p>\n<\/li>\n<li data-start=\"2746\" data-end=\"2795\">\n<p data-start=\"2748\" data-end=\"2795\">inform the doctor about all symptoms and contacts<\/p>\n<\/li>\n<li data-start=\"2796\" data-end=\"2851\">\n<p data-start=\"2798\" data-end=\"2851\">If possible, contact immediately after the appearance of ulcers<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"2853\" data-end=\"3010\">According to the recommendations <span class=\"hover:entity-accent entity-underline inline cursor-pointer align-baseline\"><span class=\"whitespace-normal\">FDA<\/span><\/span>, collecting material before starting therapy increases the diagnostic value of tests for bacterial STIs.<\/p>\n<h2 data-start=\"3012\" data-end=\"3054\">Why is it important to rule out co-infections?<\/h2>\n<p data-start=\"3056\" data-end=\"3181\">Ulcerative lesions increase the risk of HIV and other STIs. Therefore, your doctor may recommend an expanded panel of tests:<\/p>\n<ul data-start=\"3183\" data-end=\"3239\">\n<li data-start=\"3183\" data-end=\"3190\">\n<p data-start=\"3185\" data-end=\"3190\"><a href=\"https:\/\/medilab.km.ua\/en\/price\/?3325_search_1=%D1%85%D0%BB%D0%B0%D0%BC%D1%96%D0%B4%D1%96%D0%BE%D0%B7&amp;3325_device=laptop&amp;3325_orderby=relevance&amp;3325_paged=1&amp;3325_filtered=true\">OX<\/a><\/p>\n<\/li>\n<li data-start=\"3191\" data-end=\"3202\">\n<p data-start=\"3193\" data-end=\"3202\">syphilis<\/p>\n<\/li>\n<li data-start=\"3203\" data-end=\"3216\">\n<p data-start=\"3205\" data-end=\"3216\"><a href=\"https:\/\/medilab.km.ua\/en\/price\/?3325_search_1=%D1%85%D0%BB%D0%B0%D0%BC%D1%96%D0%B4%D1%96%D0%BE%D0%B7&amp;3325_device=laptop&amp;3325_orderby=relevance&amp;3325_paged=1&amp;3325_filtered=true\">chlamydia<\/a><\/p>\n<\/li>\n<li data-start=\"3217\" data-end=\"3228\">\n<p data-start=\"3219\" data-end=\"3228\">gonorrhea<\/p>\n<\/li>\n<li data-start=\"3229\" data-end=\"3239\">\n<p data-start=\"3231\" data-end=\"3239\">herpes<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"3241\" data-end=\"3313\">A comprehensive approach ensures safety and prevents repeat cases.<\/p>\n<h2 data-start=\"3315\" data-end=\"3351\">Possible complications without treatment<\/h2>\n<p data-start=\"3353\" data-end=\"3407\">Without timely treatment, soft chancre can lead to:<\/p>\n<ul data-start=\"3409\" data-end=\"3514\">\n<li data-start=\"3409\" data-end=\"3442\">\n<p data-start=\"3411\" data-end=\"3442\">suppuration of the inguinal lymph nodes<\/p>\n<\/li>\n<li data-start=\"3443\" data-end=\"3466\">\n<p data-start=\"3445\" data-end=\"3466\">abscess formation<\/p>\n<\/li>\n<li data-start=\"3467\" data-end=\"3491\">\n<p data-start=\"3469\" data-end=\"3491\">chronic inflammation<\/p>\n<\/li>\n<li data-start=\"3492\" data-end=\"3514\">\n<p data-start=\"3494\" data-end=\"3514\">contagion<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"3516\" data-end=\"3614\">Early testing for soft chancre and proper antibiotic therapy significantly reduce the risk of complications.<\/p>\n<h2 data-start=\"3616\" data-end=\"3659\">Algorithm of actions in case of suspected soft chancre<\/h2>\n<ol data-start=\"3661\" data-end=\"3917\">\n<li data-start=\"3661\" data-end=\"3695\">\n<p data-start=\"3664\" data-end=\"3695\">Do not self-medicate.<\/p>\n<\/li>\n<li data-start=\"3696\" data-end=\"3763\">\n<p data-start=\"3699\" data-end=\"3763\">Consult a dermatologist or gynecologist\/urologist.<\/p>\n<\/li>\n<li data-start=\"3764\" data-end=\"3815\">\n<p data-start=\"3767\" data-end=\"3815\">Get tested for chancroid and related STIs.<\/p>\n<\/li>\n<li data-start=\"3816\" data-end=\"3857\">\n<p data-start=\"3819\" data-end=\"3857\">Follow the prescribed treatment.<\/p>\n<\/li>\n<li data-start=\"3858\" data-end=\"3917\">\n<p data-start=\"3861\" data-end=\"3917\">Notify sexual partner and recommend testing.<\/p>\n<\/li>\n<\/ol>\n<p data-start=\"3919\" data-end=\"3977\">This approach helps break the chain of infection transmission.<\/p>\n<h2 data-start=\"3979\" data-end=\"4058\">Why a soft chancre test is part of a responsible attitude to health<\/h2>\n<p data-start=\"4060\" data-end=\"4322\">A test for soft chancre is not only a confirmation of a specific diagnosis, but also an important element in preventing complications and the spread of STIs. Laboratory diagnostics allows you to clearly distinguish a bacterial infection from other causes of ulcers and start treatment in a timely manner.<\/p>\n<p data-start=\"4324\" data-end=\"4435\">Timely and correct treatment <a href=\"https:\/\/medilab.km.ua\/en\/price\/?3325_device=laptop&amp;3325_filtered=true\">examination<\/a> \u2014 the key to a speedy recovery and maintaining reproductive health.<\/p>","protected":false},"excerpt":{"rendered":"<p>The chancroid test is a laboratory test to confirm chancroid, a sexually transmitted bacterial infection that causes painful sores.<\/p>","protected":false},"author":627,"featured_media":11414,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-11413","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"_links":{"self":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/posts\/11413","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/users\/627"}],"replies":[{"embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/comments?post=11413"}],"version-history":[{"count":0,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/posts\/11413\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/media\/11414"}],"wp:attachment":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/media?parent=11413"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/categories?post=11413"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/tags?post=11413"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}