{"id":9935,"date":"2025-06-02T17:27:34","date_gmt":"2025-06-02T14:27:34","guid":{"rendered":"https:\/\/medilab.km.ua\/?p=9935"},"modified":"2026-04-20T18:53:44","modified_gmt":"2026-04-20T15:53:44","slug":"chronic-fatigue-syndrome-is-not-a-diagnosis-of-fatigue","status":"publish","type":"post","link":"https:\/\/medilab.km.ua\/en\/chronic-fatigue-syndrome-is-not-a-diagnosis-of-fatigue\/","title":{"rendered":"Chronic fatigue syndrome: when fatigue is not a weakness, but a diagnosis"},"content":{"rendered":"<div class=\"kk-star-ratings kksr-auto kksr-align-left kksr-valign-top\"\n    data-payload='{&quot;align&quot;:&quot;left&quot;,&quot;id&quot;:&quot;9935&quot;,&quot;slug&quot;:&quot;default&quot;,&quot;valign&quot;:&quot;top&quot;,&quot;ignore&quot;:&quot;&quot;,&quot;reference&quot;:&quot;auto&quot;,&quot;class&quot;:&quot;&quot;,&quot;count&quot;:&quot;380&quot;,&quot;legendonly&quot;:&quot;&quot;,&quot;readonly&quot;:&quot;&quot;,&quot;score&quot;:&quot;4.9&quot;,&quot;starsonly&quot;:&quot;&quot;,&quot;best&quot;:&quot;5&quot;,&quot;gap&quot;:&quot;5&quot;,&quot;greet&quot;:&quot;Rate this post&quot;,&quot;legend&quot;:&quot;4.9\\\/5 - (380 votes)&quot;,&quot;size&quot;:&quot;24&quot;,&quot;title&quot;:&quot;\u0421\u0438\u043d\u0434\u0440\u043e\u043c \u0445\u0440\u043e\u043d\u0456\u0447\u043d\u043e\u0457 \u0432\u0442\u043e\u043c\u0438: \u043a\u043e\u043b\u0438 \u0432\u0442\u043e\u043c\u0430 \u2014 \u0446\u0435 \u043d\u0435 \u0441\u043b\u0430\u0431\u043a\u0456\u0441\u0442\u044c, \u0430 \u0434\u0456\u0430\u0433\u043d\u043e\u0437&quot;,&quot;width&quot;:&quot;139.6&quot;,&quot;_legend&quot;:&quot;{score}\\\/{best} - ({count} {votes})&quot;,&quot;font_factor&quot;:&quot;1.25&quot;}'>\n            \n<div class=\"kksr-stars\">\n    \n<div class=\"kksr-stars-inactive\">\n            <div class=\"kksr-star\" data-star=\"1\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"2\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"3\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"4\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"5\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n    <\/div>\n    \n<div class=\"kksr-stars-active\" style=\"width: 139.6px;\">\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 5px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 24px; height: 24px;\"><\/div>\n        <\/div>\n    <\/div>\n<\/div>\n                \n\n<div class=\"kksr-legend\" style=\"font-size: 19.2px;\">\n            4.9\/5 - (380 votes)    <\/div>\n    <\/div>\n<h2 data-start=\"425\" data-end=\"466\">This is not laziness, not depression, and not fiction.<\/h2>\n<p data-start=\"468\" data-end=\"832\">\u00ab&quot;Just get more rest,&quot; &quot;You&#039;re fine, don&#039;t exaggerate,&quot; &quot;Everyone gets tired&quot; - these phrases have been heard more than once by people who have suffered from exhaustion, pain, sleep problems, and memory problems for years. However <strong data-start=\"656\" data-end=\"689\">chronic fatigue syndrome (CFS)<\/strong> \u2014 this is not a made-up problem, but <strong data-start=\"719\" data-end=\"751\">recognized medical condition<\/strong>, which changed the idea of the boundaries between the psyche, immunity and energy metabolism.<\/p>\n<h2 data-start=\"834\" data-end=\"869\">What is chronic fatigue syndrome?<\/h2>\n<p data-start=\"871\" data-end=\"1029\">Chronic fatigue syndrome (CFS). <em data-start=\"902\" data-end=\"933\">Chronic Fatigue Syndrome, CFS<\/em>, also <em data-start=\"941\" data-end=\"968\">Myalgic Encephalomyelitis<\/em>) is <strong data-start=\"975\" data-end=\"1006\">multifactorial disease<\/strong>, which is characterized by:<\/p>\n<ul data-start=\"1031\" data-end=\"1430\">\n<li data-start=\"1031\" data-end=\"1103\">\n<p data-start=\"1033\" data-end=\"1103\"><strong data-start=\"1033\" data-end=\"1065\">constant, debilitating fatigue<\/strong>, that does not go away after sleep or rest;<\/p>\n<\/li>\n<li data-start=\"1104\" data-end=\"1201\">\n<p data-start=\"1106\" data-end=\"1201\"><strong data-start=\"1106\" data-end=\"1134\">cognitive impairment<\/strong> (clouding of consciousness, impaired concentration, forgetfulness);<\/p>\n<\/li>\n<li data-start=\"1202\" data-end=\"1318\">\n<p data-start=\"1204\" data-end=\"1318\"><strong data-start=\"1204\" data-end=\"1317\">deterioration of condition after minor physical or psycho-emotional stress (PEM - post-exertional malaise)<\/strong>;<\/p>\n<\/li>\n<li data-start=\"1319\" data-end=\"1341\">\n<p data-start=\"1321\" data-end=\"1341\"><strong data-start=\"1321\" data-end=\"1340\">sleep disorders<\/strong>;<\/p>\n<\/li>\n<li data-start=\"1342\" data-end=\"1430\">\n<p data-start=\"1344\" data-end=\"1430\"><strong data-start=\"1344\" data-end=\"1429\">headache, muscle pain, fever, sore throat, tender lymph nodes<\/strong>.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1432\" data-end=\"1526\">Duration of symptoms \u2014 <strong data-start=\"1455\" data-end=\"1481\">from 6 months and older<\/strong>, and they <strong data-start=\"1490\" data-end=\"1525\">not explained by other diseases<\/strong>.<\/p>\n<h2 data-start=\"1528\" data-end=\"1557\">How is the diagnosis made?<\/h2>\n<p data-start=\"1559\" data-end=\"1785\">The SHV is <strong data-start=\"1568\" data-end=\"1590\">diagnosis of exclusion<\/strong>, which is based on a complex of symptoms and <strong data-start=\"1633\" data-end=\"1677\">carefully ruling out other causes of fatigue<\/strong> (anemia, depression, hypothyroidism, autoimmune diseases, chronic infections, tumors, metabolic disorders, etc.).<\/p>\n<p data-start=\"1787\" data-end=\"1965\">Official diagnostic criteria have been approved <em data-start=\"1834\" data-end=\"1884\">CDC (Centers for Disease Control and Prevention)<\/em> and <em data-start=\"1888\" data-end=\"1946\">NICE (National Institute for Health and Care Excellence)<\/em>. The basis consists of:<\/p>\n<ol data-start=\"1967\" data-end=\"2178\">\n<li data-start=\"1967\" data-end=\"2036\">\n<p data-start=\"1970\" data-end=\"2036\">Fatigue lasting \u22656 months that significantly reduces activity level.<\/p>\n<\/li>\n<li data-start=\"2037\" data-end=\"2073\">\n<p data-start=\"2040\" data-end=\"2073\">Post-exertional malaise (PEM).<\/p>\n<\/li>\n<li data-start=\"2074\" data-end=\"2091\">\n<p data-start=\"2077\" data-end=\"2091\">Sleep disturbances.<\/p>\n<\/li>\n<li data-start=\"2092\" data-end=\"2178\">\n<p data-start=\"2095\" data-end=\"2178\">Additional symptoms: cognitive disorders or blood pressure dysregulation.<\/p>\n<\/li>\n<\/ol>\n<h2 data-start=\"2180\" data-end=\"2199\">What causes CVD?<\/h2>\n<p data-start=\"2201\" data-end=\"2271\">The exact cause is unknown, but <strong data-start=\"2229\" data-end=\"2270\">there are several interrelated hypotheses<\/strong>:<\/p>\n<ul data-start=\"2273\" data-end=\"2664\">\n<li data-start=\"2273\" data-end=\"2363\">\n<p data-start=\"2275\" data-end=\"2363\"><strong data-start=\"2275\" data-end=\"2312\">Viral or bacterial infection<\/strong> (Epstein-Barr virus, cytomegalovirus, SARS-CoV-2)<\/p>\n<\/li>\n<li data-start=\"2364\" data-end=\"2461\">\n<p data-start=\"2366\" data-end=\"2461\"><strong data-start=\"2366\" data-end=\"2389\">Immune dysregulation<\/strong>: increased levels of pro-inflammatory cytokines, impaired T-cell activation<\/p>\n<\/li>\n<li data-start=\"2462\" data-end=\"2536\">\n<p data-start=\"2464\" data-end=\"2536\"><strong data-start=\"2464\" data-end=\"2494\">Mitochondrial dysfunction<\/strong>: decrease in the energy potential of cells<\/p>\n<\/li>\n<li data-start=\"2537\" data-end=\"2612\">\n<p data-start=\"2539\" data-end=\"2612\"><strong data-start=\"2539\" data-end=\"2560\">Hormonal changes<\/strong> (especially the hypothalamic-pituitary-adrenal axis)<\/p>\n<\/li>\n<li data-start=\"2613\" data-end=\"2664\">\n<p data-start=\"2615\" data-end=\"2664\"><strong data-start=\"2615\" data-end=\"2645\"><a href=\"https:\/\/medilab.km.ua\/en\/chronic-stress-is-a-health-hazard-that-we-used-to-ignore\/\">Chronic stress<\/a> or trauma<\/strong> as a trigger<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"2666\" data-end=\"2778\">All of these components can run <strong data-start=\"2701\" data-end=\"2722\">pathological cycle<\/strong>, in which the body does not return to a state of recovery.<\/p>\n<h2 data-start=\"2780\" data-end=\"2817\">What tests can a doctor order?<\/h2>\n<p data-start=\"2819\" data-end=\"2878\">Although there is no \u00abSCM test,\u00bb there is a list of studies that:<\/p>\n<ol data-start=\"2880\" data-end=\"2988\">\n<li data-start=\"2880\" data-end=\"2923\">\n<p data-start=\"2883\" data-end=\"2923\">Helping <strong data-start=\"2895\" data-end=\"2922\">rule out other diagnoses<\/strong>.<\/p>\n<\/li>\n<li data-start=\"2924\" data-end=\"2988\">\n<p data-start=\"2927\" data-end=\"2988\"><strong data-start=\"2927\" data-end=\"2958\">Identify associated disorders<\/strong>, that can worsen the condition.<\/p>\n<\/li>\n<\/ol>\n<p data-start=\"2990\" data-end=\"3005\">These can be:<\/p>\n<ul data-start=\"3007\" data-end=\"3347\">\n<li data-start=\"3007\" data-end=\"3062\">\n<p data-start=\"3009\" data-end=\"3062\">Complete blood count, <a href=\"https:\/\/medilab.km.ua\/en\/analysis\/biochemical-blood-tests\/anemia-diagnosis\/ferritin\/\">ferritin<\/a>, B12, folic acid<\/p>\n<\/li>\n<li data-start=\"3063\" data-end=\"3097\">\n<p data-start=\"3065\" data-end=\"3097\"><a href=\"https:\/\/medilab.km.ua\/en\/a-blood-test-for-ttg-which-is-a-hormone-that-shows-how-the-thyroid-gland-is-working\/\">TSH<\/a>, T3, T4 (thyroid gland)<\/p>\n<\/li>\n<li data-start=\"3098\" data-end=\"3137\">\n<p data-start=\"3100\" data-end=\"3137\">Liver tests, glucose, electrolytes<\/p>\n<\/li>\n<li data-start=\"3138\" data-end=\"3185\">\n<p data-start=\"3140\" data-end=\"3185\">Inflammatory markers: CRP, ANA, antistreptolysin<\/p>\n<\/li>\n<li data-start=\"3186\" data-end=\"3238\">\n<p data-start=\"3188\" data-end=\"3238\">Herpes virus panel (EBV, CMV, HHV-6)<\/p>\n<\/li>\n<li data-start=\"3239\" data-end=\"3294\">\n<p data-start=\"3241\" data-end=\"3294\">Mitochondrial dysfunction tests (lactate, pyruvate)<\/p>\n<\/li>\n<li data-start=\"3295\" data-end=\"3347\">\n<p data-start=\"3297\" data-end=\"3347\">Neurocognitive testing (for severe complaints)<\/p>\n<\/li>\n<\/ul>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-9937\" src=\"https:\/\/medilab.km.ua\/wp-content\/uploads\/2025\/06\/vid-sboku-zensina-razgovarivaet-s-vracom.jpg\" alt=\"diagram of the causes of chronic fatigue syndrome\" width=\"1200\" height=\"800\" srcset=\"https:\/\/medilab.km.ua\/wp-content\/uploads\/2025\/06\/vid-sboku-zensina-razgovarivaet-s-vracom.jpg 1200w, https:\/\/medilab.km.ua\/wp-content\/uploads\/2025\/06\/vid-sboku-zensina-razgovarivaet-s-vracom-150x100.jpg 150w, https:\/\/medilab.km.ua\/wp-content\/uploads\/2025\/06\/vid-sboku-zensina-razgovarivaet-s-vracom-600x400.jpg 600w, https:\/\/medilab.km.ua\/wp-content\/uploads\/2025\/06\/vid-sboku-zensina-razgovarivaet-s-vracom-300x200.jpg 300w, https:\/\/medilab.km.ua\/wp-content\/uploads\/2025\/06\/vid-sboku-zensina-razgovarivaet-s-vracom-1024x683.jpg 1024w, https:\/\/medilab.km.ua\/wp-content\/uploads\/2025\/06\/vid-sboku-zensina-razgovarivaet-s-vracom-768x512.jpg 768w\" sizes=\"(max-width: 1200px) 100vw, 1200px\" \/><\/p>\n<h2 data-start=\"3349\" data-end=\"3388\">What is the treatment for chronic fatigue syndrome?<\/h2>\n<p data-start=\"3390\" data-end=\"3497\">CFS has no universal treatment, but <strong data-start=\"3431\" data-end=\"3459\">improvement is possible<\/strong>, especially with an individual approach:<\/p>\n<ul data-start=\"3499\" data-end=\"3963\">\n<li data-start=\"3499\" data-end=\"3569\">\n<p data-start=\"3501\" data-end=\"3569\"><strong data-start=\"3501\" data-end=\"3512\">Pacing<\/strong> (energy dosage of activity): learning to avoid PEM<\/p>\n<\/li>\n<li data-start=\"3570\" data-end=\"3649\">\n<p data-start=\"3572\" data-end=\"3649\"><strong data-start=\"3572\" data-end=\"3606\">Cognitive behavioral therapy<\/strong> (CBT): effective for anxiety component<\/p>\n<\/li>\n<li data-start=\"3650\" data-end=\"3739\">\n<p data-start=\"3652\" data-end=\"3739\"><strong data-start=\"3652\" data-end=\"3680\">Pharmacological support<\/strong>: symptomatic treatment of pain, anxiety, sleep, inflammation<\/p>\n<\/li>\n<li data-start=\"3740\" data-end=\"3815\">\n<p data-start=\"3742\" data-end=\"3815\"><strong data-start=\"3742\" data-end=\"3768\">Mitosupportive therapy<\/strong>: coenzyme Q10, carnitine, NADH, B vitamins<\/p>\n<\/li>\n<li data-start=\"3816\" data-end=\"3891\">\n<p data-start=\"3818\" data-end=\"3891\"><strong data-start=\"3818\" data-end=\"3843\">Anti-inflammatory supplements<\/strong>: omega-3, curcumin, resveratrol (if indicated)<\/p>\n<\/li>\n<li data-start=\"3892\" data-end=\"3963\">\n<p data-start=\"3894\" data-end=\"3963\"><strong data-start=\"3894\" data-end=\"3922\">Work with a psychotherapist<\/strong> \u2014 important, but <strong data-start=\"3938\" data-end=\"3963\">not as a replacement for a diagnosis<\/strong><\/p>\n<\/li>\n<\/ul>\n<h2 data-start=\"3965\" data-end=\"3999\">Is CFS associated with Long COVID?<\/h2>\n<p data-start=\"4001\" data-end=\"4307\">Yes. After suffering from COVID-19, a significant proportion of patients report <strong data-start=\"4074\" data-end=\"4137\">prolonged fatigue, muscle pain, head fog, sleep disturbances<\/strong>, which fully corresponds to the description of CFS. Therefore, Long COVID is considered as <strong data-start=\"4206\" data-end=\"4240\">trigger form of chronic fatigue<\/strong>, which may require the same approach to diagnosis and treatment.<\/p>\n<h2 data-start=\"4309\" data-end=\"4375\">CFS is a real disease that requires real treatment<\/h2>\n<p data-start=\"4377\" data-end=\"4655\">It is important to recognize that SCD is not a psychological weakness, a lack of motivation, or a fabrication. It is <strong data-start=\"4478\" data-end=\"4522\">a condition that significantly affects quality of life<\/strong>, and for which you need <strong data-start=\"4545\" data-end=\"4576\">multidisciplinary approach<\/strong> \u2014 from a family doctor, neurologist, psychotherapist, immunologist, nutritionist.<\/p>\n<h2 data-start=\"4657\" data-end=\"4687\">And most importantly, you are not alone.<\/h2>\n<p data-start=\"4689\" data-end=\"4897\">Hundreds of thousands of people around the world are going through the same symptoms. Diagnosis can be difficult, but the road to recovery starts with the first \u2014 <strong data-start=\"4836\" data-end=\"4896\">recognition that it&#039;s not &quot;in your head&quot; but in your body<\/strong>.<\/p>","protected":false},"excerpt":{"rendered":"<p>This is not laziness, not depression, and not a fabrication: \u00abJust rest more,\u00bb \u00abYou\u2019re fine, don\u2019t exaggerate,\u00bb \u00abEveryone gets tired.\u00bb<\/p>","protected":false},"author":627,"featured_media":9936,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-9935","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u0421\u0438\u043d\u0434\u0440\u043e\u043c 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