{"id":9949,"date":"2025-06-08T20:52:25","date_gmt":"2025-06-08T17:52:25","guid":{"rendered":"https:\/\/medilab.km.ua\/?p=9949"},"modified":"2026-07-01T04:22:00","modified_gmt":"2026-07-01T01:22:00","slug":"determination-of-vitamin-d-levels-in-the-clinical-situation-that-revealed-the-underlying-problem","status":"publish","type":"post","link":"https:\/\/medilab.km.ua\/en\/determination-of-vitamin-d-levels-in-the-clinical-situation-that-revealed-the-underlying-problem\/","title":{"rendered":"Vitamin K Level Determination: A Clinical Situation That Revealed a Hidden Problem"},"content":{"rendered":"<h2 data-start=\"497\" data-end=\"523\">Case: bruises for no reason<\/h2>\n<p data-start=\"525\" data-end=\"821\">Anna, 43 years old, went to the doctor with complaints of <strong data-start=\"576\" data-end=\"608\">frequent bruising on the legs and arms<\/strong>, which appear without strokes. She was also worried about <strong data-start=\"657\" data-end=\"680\">bleeding gums<\/strong> while brushing teeth. Complete blood count \u2014 no changes. Clotting time is prolonged. The doctor prescribed <strong data-start=\"781\" data-end=\"820\">blood test for vitamin K levels<\/strong>.<\/p>\n<h2 data-start=\"823\" data-end=\"844\">What did the analysis show?<\/h2>\n<p data-start=\"846\" data-end=\"1068\">Vitamin K1 (phylloquinone) level \u2014 <strong data-start=\"879\" data-end=\"893\">0.08 ng\/ml<\/strong>, that <strong data-start=\"898\" data-end=\"926\">below the lower limit of normal<\/strong>. Additionally, it turned out that Anna does not eat green vegetables and has been taking a tetracycline antibiotic for several months after chronic sinusitis.<\/p>\n<h2 data-start=\"1070\" data-end=\"1087\">What does this mean?<\/h2>\n<p data-start=\"1089\" data-end=\"1318\">Vitamin K is key for <strong data-start=\"1114\" data-end=\"1150\">synthesis of blood clotting factors<\/strong>. Its deficiency may remain <strong data-start=\"1181\" data-end=\"1202\">unnoticed for years<\/strong>, but with a combination of diet, medication, and gut condition <strong data-start=\"1261\" data-end=\"1317\">leads to bleeding and the threat of hemorrhage<\/strong>.<\/p>\n<h2 data-start=\"1325\" data-end=\"1360\">What do you need to know about vitamin K?<\/h2>\n<ul data-start=\"1362\" data-end=\"1622\">\n<li data-start=\"1362\" data-end=\"1434\">\n<p data-start=\"1364\" data-end=\"1434\"><strong data-start=\"1364\" data-end=\"1378\">Vitamin K1<\/strong> comes with green vegetables (spinach, broccoli, lettuce).<\/p>\n<\/li>\n<li data-start=\"1435\" data-end=\"1500\">\n<p data-start=\"1437\" data-end=\"1500\"><strong data-start=\"1437\" data-end=\"1451\">Vitamin K2<\/strong> (menaquinone) is produced by bacteria in the intestine.<\/p>\n<\/li>\n<li data-start=\"1501\" data-end=\"1622\">\n<p data-start=\"1503\" data-end=\"1622\">He <strong data-start=\"1507\" data-end=\"1548\">does not accumulate in large quantities<\/strong>, therefore, deficiency develops rapidly when absorption or synthesis is impaired.<\/p>\n<\/li>\n<\/ul>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-9951\" src=\"https:\/\/medilab.km.ua\/wp-content\/uploads\/2025\/06\/K-vitamini.jpg\" alt=\"greens and broccoli as a source of vitamin K\" width=\"1200\" height=\"675\" srcset=\"https:\/\/medilab.km.ua\/wp-content\/uploads\/2025\/06\/K-vitamini.jpg 1200w, https:\/\/medilab.km.ua\/wp-content\/uploads\/2025\/06\/K-vitamini-150x84.jpg 150w, https:\/\/medilab.km.ua\/wp-content\/uploads\/2025\/06\/K-vitamini-600x338.jpg 600w, https:\/\/medilab.km.ua\/wp-content\/uploads\/2025\/06\/K-vitamini-300x169.jpg 300w, https:\/\/medilab.km.ua\/wp-content\/uploads\/2025\/06\/K-vitamini-1024x576.jpg 1024w, https:\/\/medilab.km.ua\/wp-content\/uploads\/2025\/06\/K-vitamini-768x432.jpg 768w\" sizes=\"(max-width: 1200px) 100vw, 1200px\" \/><\/p>\n<h2 data-start=\"1629\" data-end=\"1667\">Who is most at risk of having a deficiency?<\/h2>\n<ul data-start=\"1669\" data-end=\"1957\">\n<li data-start=\"1669\" data-end=\"1727\">\n<p data-start=\"1671\" data-end=\"1727\">People on <strong data-start=\"1679\" data-end=\"1727\">high-fat diets or poor nutrition<\/strong><\/p>\n<\/li>\n<li data-start=\"1728\" data-end=\"1785\">\n<p data-start=\"1730\" data-end=\"1785\">Patients with <strong data-start=\"1741\" data-end=\"1785\">pathology of the liver, biliary tract<\/strong><\/p>\n<\/li>\n<li data-start=\"1786\" data-end=\"1834\">\n<p data-start=\"1788\" data-end=\"1834\">Those who accept <strong data-start=\"1804\" data-end=\"1834\">antibiotics for more than 10 days<\/strong><\/p>\n<\/li>\n<li data-start=\"1835\" data-end=\"1896\">\n<p data-start=\"1837\" data-end=\"1896\">People who use <strong data-start=\"1856\" data-end=\"1896\">anticoagulants (e.g., warfarin)<\/strong><\/p>\n<\/li>\n<li data-start=\"1897\" data-end=\"1957\">\n<p data-start=\"1899\" data-end=\"1957\"><strong data-start=\"1899\" data-end=\"1916\">Newborns<\/strong>, who were not given vitamin K prophylactically<\/p>\n<\/li>\n<\/ul>\n<h2 data-start=\"1964\" data-end=\"1988\">How to check the level?<\/h2>\n<p data-start=\"1990\" data-end=\"2141\">Analysis requires <a href=\"https:\/\/medilab.km.ua\/en\/how-to-prepare-a-baby-for-blood-collection-without-any-injuries\/\" title=\"How to prepare a child for blood sampling to avoid injury\"  data-wpil-monitor-id=\"89\">venous blood sampling<\/a> <strong data-start=\"2027\" data-end=\"2041\">on an empty stomach<\/strong>. It is advisable to combine it with <a href=\"https:\/\/medilab.km.ua\/en\/analysis\/study-of-blood-clotting-functions\/coagulogram\/\"><strong data-start=\"2068\" data-end=\"2085\">coagulogram<\/strong> <\/a>or <a href=\"https:\/\/medilab.km.ua\/en\/analysis\/study-of-blood-clotting-functions\/mnv-inr\/\"><strong data-start=\"2090\" data-end=\"2097\">INR<\/strong><\/a>, to assess the functional impact of the deficit.<\/p>\n<blockquote data-start=\"2143\" data-end=\"2286\">\n<p data-start=\"2145\" data-end=\"2286\"><strong data-start=\"2145\" data-end=\"2192\">Normal values of phylloquinone (vitamin K1):<\/strong><br data-start=\"2192\" data-end=\"2195\" \/>Adults \u2014 <strong data-start=\"2207\" data-end=\"2224\">0.1\u20132.2 ng\/ml<\/strong><br data-start=\"2224\" data-end=\"2227\" \/>Newborns \u2014 &lt;0.1 (without prophylaxis \u2014 always reduced)<\/p>\n<\/blockquote>\n<h2 data-start=\"2293\" data-end=\"2326\">What to do if the level is low?<\/h2>\n<ul data-start=\"2328\" data-end=\"2654\">\n<li data-start=\"2328\" data-end=\"2414\">\n<p data-start=\"2330\" data-end=\"2414\">Enter <strong data-start=\"2337\" data-end=\"2355\">dietary changes<\/strong> \u2014 eat more broccoli, spinach, cabbage, soy, parsley.<\/p>\n<\/li>\n<li data-start=\"2415\" data-end=\"2487\">\n<p data-start=\"2417\" data-end=\"2487\">Avoid <strong data-start=\"2425\" data-end=\"2460\">excessive use of antibiotics<\/strong>, especially without probiotics.<\/p>\n<\/li>\n<li data-start=\"2488\" data-end=\"2563\">\n<p data-start=\"2490\" data-end=\"2563\">If necessary - <strong data-start=\"2504\" data-end=\"2562\">prescribing vitamin K in the form of a drug or complex<\/strong>.<\/p>\n<\/li>\n<li data-start=\"2564\" data-end=\"2654\">\n<p data-start=\"2566\" data-end=\"2654\">If you are taking anticoagulants \u2014 <strong data-start=\"2598\" data-end=\"2653\">do not change your diet abruptly without consulting your doctor<\/strong>.<\/p>\n<\/li>\n<\/ul>\n<h2 data-start=\"2661\" data-end=\"2679\">Doctor&#039;s comment<\/h2>\n<blockquote data-start=\"2681\" data-end=\"3005\">\n<p data-start=\"2683\" data-end=\"3005\">\u201cWe often underestimate the role of vitamin K. Unlike iron or vitamin D, its deficiency does not have classic symptoms, but it increases the risk <strong data-start=\"2820\" data-end=\"2849\">unexpected bleeding<\/strong>, especially in patients with chronic liver disease or on long-term treatment. This is a marker that should be paid attention to even in a routine examination.\u201d<\/p>\n<\/blockquote>\n<h2 data-start=\"3012\" data-end=\"3032\">How is Anna doing?<\/h2>\n<p data-start=\"3034\" data-end=\"3257\">After correcting the diet and prescribing vitamin K1 (10 mg\/week), the level stabilized after just 2 weeks. <strong data-start=\"3143\" data-end=\"3192\">The bruises disappeared, blood clotting normalized.<\/strong>, and the doctor advised to repeat the control in 3 months - in dynamics.<\/p>","protected":false},"excerpt":{"rendered":"<p>Case: Bruises for no reason Anna, 43 years old, went to the doctor complaining of frequent bruises on her legs and arms, which<\/p>","protected":false},"author":627,"featured_media":9950,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-9949","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zahvoryuvannya-ta-symptomy"],"_links":{"self":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/posts\/9949","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/users\/627"}],"replies":[{"embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/comments?post=9949"}],"version-history":[{"count":1,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/posts\/9949\/revisions"}],"predecessor-version":[{"id":13892,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/posts\/9949\/revisions\/13892"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/media\/9950"}],"wp:attachment":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/media?parent=9949"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/categories?post=9949"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/tags?post=9949"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}