{"id":10860,"date":"2025-11-27T19:59:38","date_gmt":"2025-11-27T17:59:38","guid":{"rendered":"https:\/\/medilab.km.ua\/?post_type=product&#038;p=10860"},"modified":"2025-12-20T14:37:54","modified_gmt":"2025-12-20T12:37:54","slug":"papillary-nipple-biopsy","status":"publish","type":"product","link":"https:\/\/medilab.km.ua\/en\/analysis\/pathomorphological-study\/papillary-nipple-biopsy\/","title":{"rendered":"Biopsy of the Vater nipple"},"content":{"rendered":"<p data-path-to-node=\"1\"><b data-path-to-node=\"1\" data-index-in-node=\"0\">Biopsy of the Vater nipple<\/b> \u2014 is the taking of a tissue sample from the confluence of the common bile duct and pancreatic duct into the duodenum. This is a technically complex and extremely responsible study performed during endoscopy (EGD or ERCP) for the differential diagnosis between benign changes and tumors in this area.<\/p>\n<p data-path-to-node=\"2\"><b data-path-to-node=\"2\" data-index-in-node=\"0\">Research objective:<\/b> The main task is to determine the cause of the obstruction of bile or pancreatic secretion. Since the papilla of Vater has a complex anatomical structure, pathomorphological analysis is the only way to distinguish inflammatory edema (papilitis) or stenosis from adenoma or cancer (ampullary carcinoma).<\/p>\n<p data-path-to-node=\"3\"><b data-path-to-node=\"3\" data-index-in-node=\"0\">What does the pathologist evaluate:<\/b><\/p>\n<ul data-path-to-node=\"4\">\n<li>\n<p data-path-to-node=\"4,0,0\"><b data-path-to-node=\"4,0,0\" data-index-in-node=\"0\">Epithelium type:<\/b> assessment of changes in the mucous membrane in the ampulla area.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"4,1,0\"><b data-path-to-node=\"4,1,0\" data-index-in-node=\"0\">Presence of adenoma:<\/b> detection of benign growths that have a high potential to degenerate into cancer.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"4,2,0\"><b data-path-to-node=\"4,2,0\" data-index-in-node=\"0\">Signs of malignancy:<\/b> search for atypical cells indicating the development of adenocarcinoma.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"4,3,0\"><b data-path-to-node=\"4,3,0\" data-index-in-node=\"0\">Degree of dysplasia:<\/b> assessment of precancerous changes in nipple tissues.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"4,4,0\"><b data-path-to-node=\"4,4,0\" data-index-in-node=\"0\">Inflammatory changes:<\/b> diagnosis of chronic papillitis, which can cause mechanical jaundice.<\/p>\n<\/li>\n<\/ul>\n<p data-path-to-node=\"5\"><b data-path-to-node=\"5\" data-index-in-node=\"0\">Clinical significance:<\/b> The biopsy results determine the radicality of further treatment. If a benign adenoma is detected, its endoscopic removal (papilectomy) is possible. If a malignant process is confirmed, the patient usually requires a complex surgical operation (pancreatoduodenal resection).<\/p>\n<p data-path-to-node=\"6\"><b data-path-to-node=\"6\" data-index-in-node=\"0\">When is it prescribed:<\/b><\/p>\n<ul data-path-to-node=\"7\">\n<li>\n<p data-path-to-node=\"7,0,0\">visual thickening, deformation, or enlargement of the nipple of Vater during endoscopy;<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"7,1,0\">mechanical jaundice of unknown origin;<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"7,2,0\">dilation of the bile or pancreatic ducts according to ultrasound, MRI or CT scan;<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"7,3,0\">suspected tumor of the ampullary zone;<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"7,4,0\">control after endoscopic removal of neoplasms of this location.<\/p>\n<\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p><strong>Histological material is taken only in medical institutions.<\/strong><\/p>","protected":false},"featured_media":11125,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[223,227],"product_tag":[],"class_list":["post-10860","product","type-product","status-publish","has-post-thumbnail","product_cat-patomorfologichni-doslidzhennya","product_cat-endoskopichni-doslidzhennya","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product\/10860","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/comments?post=10860"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/media\/11125"}],"wp:attachment":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/media?parent=10860"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product_brand?post=10860"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product_cat?post=10860"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product_tag?post=10860"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}