S-100 protein<\/strong>, in particular his faction S100B<\/strong>, is a protein associated mainly with cells of the nervous system and some other cells of the body. Determining its concentration in the blood can be used in oncology and neurology as additional laboratory indicator<\/strong>.<\/p>\n S100B levels may be elevated in patients with melanoma, especially in advanced disease. Therefore, the study can be used to further assess the patient's condition and monitor the course of already diagnosed melanoma.<\/p>\n At the same time, S100B is not a specific tumor marker. It is not possible to establish or rule out melanoma based on a single test result.<\/strong><\/p>\n The study can be used:<\/p>\n S100B can be used as an additional marker in patients with melanoma. Its elevation is more likely to be significant in common forms of the disease<\/strong>, however, the result cannot be used as an independent diagnostic method.<\/p>\n Skin examination, dermatoscopy, and, if necessary, histological examination of the lesion are essential for detecting and confirming melanoma.<\/p>\n S100B is associated with nerve tissue cells, so changes in its concentration can be observed in various conditions accompanied by damage to nerve tissue.<\/p>\n An elevated index can occur in various neurological and other pathological conditions, therefore By itself, it does not determine the cause of CNS damage and does not replace a neurological examination, MRI, CT scan, or other necessary tests.<\/strong><\/p>\n Elevated S100B levels can have various causes, including common cancers, such as melanoma, and conditions that involve damage to nerve tissue.<\/p>\n Therefore, the result must be evaluated in the context of a clinical situation<\/strong>. One elevated reading does not automatically mean the presence of malignant disease or brain damage.<\/p>\n Venous blood (serum).<\/strong><\/p>\n To obtain a reliable result, it is recommended:<\/p>\n If the analysis is submitted at the same time as other laboratory tests, the laboratory's general fasting requirements must be followed.<\/p>\n If the test is ordered in connection with melanoma, it is advisable to perform it in dynamics on the recommendation of a doctor<\/strong>, so that the results can be compared with each other.<\/p>\n For disease control, not only S100B is important, but also a complex of data: the results of examination, histology, imaging studies, and other laboratory parameters.<\/p>\n It is not recommended to independently interpret elevated S-100 as a sign of cancer.<\/strong> The result should be evaluated by a doctor taking into account the history and other examinations.<\/p>\n S-100B is not a stand-alone test for melanoma screening in healthy people.<\/strong> This is an additional laboratory indicator that acquires the greatest clinical significance with the correct choice of indications and a comprehensive assessment of the results.<\/p>","protected":false},"excerpt":{"rendered":" Tumor marker protein S-100 (S100B)<\/strong> \u2014 laboratory study of the level of S-100 protein in the blood. The indicator can be used as additional marker in melanoma<\/strong>, in particular to assess the course of the disease, as well as in the comprehensive assessment of some conditions associated with damage to the central nervous system.<\/p>\n Importantly:<\/strong> Elevated S-100 levels are not specific for melanoma or brain damage. The result is evaluated in conjunction with symptoms, examination data, and other laboratory parameters.<\/p>","protected":false},"featured_media":15070,"comment_status":"open","ping_status":"closed","template":"","meta":{"_flow_reviewer_id":0,"_flow_review_status":""},"product_brand":[],"product_cat":[105],"product_tag":[],"class_list":["post-12370","product","type-product","status-publish","has-post-thumbnail","product_cat-diagnostyka-puhlynnyh-markeriv","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product\/12370","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/comments?post=12370"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/media\/15070"}],"wp:attachment":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/media?parent=12370"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product_brand?post=12370"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product_cat?post=12370"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product_tag?post=12370"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}When is the analysis prescribed?<\/h3>\n
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S-100 and melanoma<\/h3>\n
S-100 and the central nervous system<\/h3>\n
What could an elevated result mean?<\/h3>\n
Biomaterial<\/h3>\n
Preparation for analysis<\/h3>\n
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Recommendations<\/h3>\n
Importantly<\/h3>\n
Brief description of the product<\/h2>\n