{"id":3711,"date":"2021-03-12T13:17:42","date_gmt":"2021-03-12T11:17:42","guid":{"rendered":"https:\/\/medilab.km.ua\/?post_type=product&p=3711"},"modified":"2026-10-04T15:10:38","modified_gmt":"2026-10-04T12:10:38","slug":"rheumatism-panel-14-antigens","status":"publish","type":"product","link":"https:\/\/medilab.km.ua\/en\/analizy\/autoimunologiya\/revma-panel-14-antygeniv\/","title":{"rendered":"Rheumatoid arthritis panel (14 antigens)"},"content":{"rendered":"

Autoimmune diseases are one of the most mysterious and complex problems of modern medicine. They arise when the body's immune system attacks its own cells and tissues, viewing them as foreign agents. Among these diseases, rheumatoid arthritis, systemic lupus erythematosus, and scleroderma are among the most common.<\/p>\n

To properly diagnose and monitor autoimmune diseases, doctors use various methods, one of which is the rheumatology panel. This the panel consists of 14 antigens<\/a>, which help determine the presence of an autoimmune process in the body and establish a specific diagnosis.<\/p>\n

The composition of the rheumatology panel includes the following antigens:<\/p>\n

    \n
  1. Rheumatoid factor (RF) is an antibody that is often found in rheumatoid arthritis. Elevated levels of RF may indicate an exacerbation of the disease.<\/li>\n
  2. Antinuclear antibodies (ANA) \u2013 their elevated levels can be a sign of systemic lupus erythematosus, lupus, and other diseases.<\/li>\n
  3. Antibodies to cyclic citrullinated peptide (anti-CCP) \u2013 their elevated levels indicate possible rheumatoid arthritis.<\/li>\n
  4. Antibodies to the nuclear antigen RNP (anti-RNP) \u2013 this may be an indicator of systemic lupus erythematosus.<\/li>\n
  5. Antibodies to DNA (anti-dsDNA) \u2013 their elevated levels are often found in patients with lupus.<\/li>\n
  6. Antibodies to nuclear antigens Sm (anti-Sm) \u2013 their presence may be an indicator of lupus.<\/li>\n
  7. Antibodies to neutrophil cytoplasmic antigens (ANCA) \u2013 these may be associated with vasculitis.<\/li>\n
  8. Antibodies to glomerular basement membrane (anti-GBM) \u2013 may indicate glomerulonephritis.<\/li>\n
  9. Antiphospholipid antibodies (anticardiolipin, beta-2-glycoprotein antibodies) \u2013 these may be associated with antiphospholipid syndrome.<\/li>\n
  10. Antibodies to Scl-70 \u2013 their elevated level indicates possible scleroderma.<\/li>\n
  11. Anti-centromere antibodies \u2013 this may be an indicator of systemic scleroderma.<\/li>\n
  12. Antibodies to Jo-1 \u2013 their presence may be a sign of dermatomyositis.<\/li>\n
  13. Antibodies to nuclear antigen peptides (anti-histone) \u2013 may be associated with lupus and some other diseases.<\/li>\n
  14. Antitrypsin antibodies (anti-PM-Scl) \u2013 these may be associated with systemic scleroderma.<\/li>\n<\/ol>\n

    The rheumatology panel helps doctors determine which antigens are present in a patient and use this to make a diagnosis. It is important to note that the results of the rheumatology panel are always evaluated in the context of clinical symptoms and other tests.<\/p>\n

    Conclusion: The rheumatology panel is an important tool in the diagnosis of autoimmune diseases, as well as in determining the effectiveness of treatment and disease control. It allows doctors to more accurately and individually prepare a treatment plan for each patient, which contributes to improving the quality of life and prognosis for patients with autoimmune diseases.<\/p>","protected":false},"excerpt":{"rendered":"

    Rheumatoid arthritis panel (14 antigens)<\/strong> \u2014 a comprehensive immunological study to determine autoantibodies associated with systemic connective tissue diseases, including systemic lupus erythematosus, Sj\u00f6gren's syndrome, systemic scleroderma, polymyositis, and dermatomyositis.<\/p>\n

    The study includes:<\/strong><\/p>\n

      \n
    • Ro\/SS-A 52<\/strong> \u2014 antibodies associated with Sj\u00f6gren's syndrome and other systemic autoimmune diseases.<\/li>\n
    • Jo-1<\/strong> \u2014 a marker associated with inflammatory myopathies.<\/li>\n
    • Sm<\/strong> \u2014 antibodies characteristic of systemic lupus erythematosus.<\/li>\n
    • CENP-B<\/strong> \u2014 antibodies associated with systemic scleroderma, in particular CREST syndrome.<\/li>\n
    • La\/SS-B<\/strong> \u2014 antibodies associated with Sj\u00f6gren's syndrome.<\/li>\n
    • Histone<\/strong> \u2014 antibodies that can be detected in drug-induced lupus and other autoimmune conditions.<\/li>\n
    • PM\/Scl 100<\/strong> \u2014 antibodies associated with a combination of features of systemic scleroderma and inflammatory myopathy.<\/li>\n
    • Rib Phosphoprotein Po<\/strong> \u2014 antibodies that may be associated with systemic lupus erythematosus.<\/li>\n
    • dsDNA<\/strong> \u2014 antibodies to double-stranded DNA, important for the evaluation of systemic lupus erythematosus.<\/li>\n
    • Scl-70<\/strong> \u2014 antibodies associated with systemic scleroderma.<\/li>\n
    • U1-snRNP<\/strong> \u2014 antibodies that can be detected in mixed connective tissue diseases.<\/li>\n
    • Ro\/SS-A 60<\/strong> \u2014 antibodies associated with Sj\u00f6gren's syndrome and systemic lupus erythematosus.<\/li>\n
    • Mi-2<\/strong> \u2014 antibodies associated with dermatomyositis.<\/li>\n
    • Ku<\/strong> \u2014 antibodies that can be detected in systemic connective tissue diseases and inflammatory myopathies.<\/li>\n<\/ul>\n

      When is the study prescribed?<\/strong><\/p>\n

      The test may be recommended by a doctor if a systemic autoimmune disease is suspected, including persistent joint pain or inflammation, muscle weakness, rashes, Raynaud's phenomenon, or other signs of connective tissue damage. The results are evaluated along with symptoms, physical examination, and other laboratory and instrumental studies. It is not possible to independently confirm the diagnosis based on a single positive autoantibody.<\/p>","protected":false},"featured_media":16030,"comment_status":"open","ping_status":"closed","template":"","meta":{"_flow_reviewer_id":0,"_flow_review_status":""},"product_brand":[],"product_cat":[145],"product_tag":[],"class_list":["post-3711","product","type-product","status-publish","has-post-thumbnail","product_cat-autoimunologiya","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product\/3711","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/comments?post=3711"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/media\/16030"}],"wp:attachment":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/media?parent=3711"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product_brand?post=3711"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product_cat?post=3711"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product_tag?post=3711"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}