{"id":9973,"date":"2025-07-07T14:29:01","date_gmt":"2025-07-07T11:29:01","guid":{"rendered":"https:\/\/medilab.km.ua\/?post_type=product&#038;p=9973"},"modified":"2026-05-27T11:55:48","modified_gmt":"2026-05-27T08:55:48","slug":"gepatyt-d-hdv-real-time-pcr-kilkisne-vyznachennya","status":"publish","type":"product","link":"https:\/\/medilab.km.ua\/en\/analysis\/infectious-disease-panel\/gepatyt-d-hdv-real-time-pcr-kilkisne-vyznachennya\/","title":{"rendered":"Hepatitis D (HDV): Real-time PCR-quantitative determination"},"content":{"rendered":"<div id=\"model-response-message-contentr_43de13bd04b3ea90\" class=\"markdown markdown-main-panel enable-updated-hr-color\" dir=\"ltr\">\n<p>Hepatitis D (HDV) is a unique viral liver disease that can only occur in the presence of hepatitis B virus (HBV). Hepatitis D is a \u201cdefective\u201d virus that requires the hepatitis B virus envelope to replicate and spread. This means that HDV infection is only possible in people who are already carriers of HBV or are co-infected with both viruses. Hepatitis D is considered the most severe form of viral hepatitis because it significantly accelerates the progression of liver disease, increasing the risk of cirrhosis, liver failure, and hepatocellular carcinoma.<\/p>\n<p>&nbsp;<\/p>\n<h3>Why is HDV quantification critical?<\/h3>\n<p>&nbsp;<\/p>\n<p>Real-time PCR \u2013 quantitative determination of hepatitis D virus (HDV) \u2013 is  <a href=\"https:\/\/medilab.km.ua\/en\/parvovirus-b19-and-current-laboratory-diagnosis-of-infection\/\"> modern and highly sensitive method of laboratory diagnostics, <\/a>  which allows not only to detect the presence of the virus in the blood, but also to determine its quantity (also learn more about other viral studies: parvovirus B19 and modern laboratory diagnostics of the infection). A similar approach is used for other dangerous infections, for example, when <b data-path-to-node=\"8,1,1,0\" data-index-in-node=\"350\"><a class=\"ng-star-inserted\" href=\"https:\/\/www.google.com\/search?q=https:\/\/medilab.km.ua\/parvovirus-b19-diagnostyka\/\" target=\"_blank\" rel=\"noopener\" data-hveid=\"0\" data-ved=\"0CAAQ_4QMahgKEwi0lveBwtuVAxUAAAAAHQAAAAAQkgE\">laboratory diagnostics of parvovirus B19<\/a><\/b>, which allows for timely detection of the pathogen. This is crucial for:<\/p>\n<ol start=\"1\">\n<li><b>Diagnostics of active infection:<\/b> Detection of HDV RNA confirms active viral replication.<\/li>\n<li><b>Disease severity assessments:<\/b> High viral load often correlates with a more aggressive course of hepatitis D and faster progression of liver damage.<\/li>\n<li><b>Monitoring the effectiveness of treatment:<\/b> Quantification allows for assessment of response to antiviral therapy by monitoring the reduction in viral load.<\/li>\n<li><b>Predicting the course of the disease:<\/b> Changes in viral load can indicate the dynamics of the disease and the risk of developing complications.<\/li>\n<\/ol>\n<p>\u0423 <b>Medilab Plus laboratories<\/b>\u00a0We offer highly accurate quantitative determination of HDV by Real-time PCR, providing reliable results for effective disease management.<\/p>\n<p>&nbsp;<\/p>\n<h3>Who is recommended to take the HDV Real-time PCR test?<\/h3>\n<p>&nbsp;<\/p>\n<p>This <b>analysis<\/b> is mandatory for all patients diagnosed or suspected of being infected with the hepatitis B virus. In particular, it is recommended <b>to hand over<\/b> in the following cases:<\/p>\n<ul>\n<li><b>All patients with positive HBsAg (hepatitis B virus surface antigen):<\/b> This is the main risk group because HDV cannot exist without HBV.<\/li>\n<li><b>Patients with chronic hepatitis B and unexplained liver deterioration:<\/b> Rapid progression of fibrosis or cirrhosis despite HBV treatment may indicate HDV coinfection.<\/li>\n<li><b>Individuals with elevated liver enzyme levels (ALT, AST) without an obvious cause who are carriers of HBsAg.<\/b><\/li>\n<li><b>Patients with acute hepatitis, especially if HBV\/HDV coinfection is suspected.<\/b><\/li>\n<li><b>To monitor the effectiveness of antiviral therapy in patients with diagnosed hepatitis D.<\/b><\/li>\n<li><b>People at risk of viral hepatitis infection:<\/b>\n<ul>\n<li>Injecting drug users.<\/li>\n<li>Persons who received transfusions of blood or its components before 1992.<\/li>\n<li>Patients on hemodialysis.<\/li>\n<li>Healthcare workers in contact with blood.<\/li>\n<li>Individuals who have unprotected sexual contact with HBV carriers.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>Advantages of Real-time PCR at Medilab Plus:<\/h3>\n<p>&nbsp;<\/p>\n<ul>\n<li><b>High sensitivity and specificity:<\/b> The Real-time PCR method allows the detection of even minimal amounts of viral RNA, which is critically important for early diagnosis and monitoring.<\/li>\n<li><b>Quantification:<\/b> Obtaining an accurate viral load allows doctors to objectively assess viral activity and the effectiveness of treatment.<\/li>\n<li><b>Speed of obtaining results:<\/b> Real-time PCR technology provides relatively fast performance <b>analysis<\/b>, which allows for rapid clinical decision-making.<\/li>\n<li><b>Reliability:<\/b> The use of modern equipment and compliance with international quality standards ensure high reliability of results.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>Preparation for analysis:<\/h3>\n<p>&nbsp;<\/p>\n<p>For conducting <a href=\"https:\/\/medilab.km.ua\/en\/before-you-pass-the-analysis-you-need-to-know\/\" title=\"Before taking the tests, you need to know\"  data-wpil-monitor-id=\"415\">HDV Real-time PCR analysis is necessary<\/a> <b>provide a venous blood sample. Special preparation (e.g. fasting) is usually not required, but it is recommended to clarify this with our specialists when making an appointment. <b>analysis<\/b>.<\/p>\n<p>&nbsp;<\/p>\n<h3>Interpretation of results:<\/h3>\n<p>&nbsp;<\/p>\n<ul>\n<li><b>Detection of HDV RNA:<\/b> Indicates active viral replication and the presence of hepatitis D. The quantitative indicator (copies\/ml or IU\/ml) indicates the viral load.<\/li>\n<li><b>No HDV RNA detected:<\/b> In the absence of clinical symptoms and other markers of activity, this may indicate the absence of active infection or a successful response to treatment.<\/li>\n<\/ul>\n<p>Interpretation of results should always be carried out by a doctor in conjunction with the clinical picture, medical history and results of other laboratory tests (HBV markers, liver tests, liver ultrasound, etc.).<\/p>\n<p><b>Take the test<\/b> Hepatitis D (HDV): Real-time PCR \u2013 quantitative determination in <b>Medilab Plus laboratories<\/b> and get accurate information to effectively monitor the condition of your liver. Your health is our priority.<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Infectious panel\/Hepatitis\/Hepatitis D (HDV)<\/p>\n<p><strong>Quantification<\/strong><\/p>","protected":false},"featured_media":10134,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[106,111,107],"product_tag":[],"class_list":["post-9973","product","type-product","status-publish","has-post-thumbnail","product_cat-infektsijna-panel","product_cat-gepatyt-d-hdv","product_cat-gepatyty","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product\/9973","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/comments?post=9973"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/media\/10134"}],"wp:attachment":[{"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/media?parent=9973"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product_brand?post=9973"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product_cat?post=9973"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medilab.km.ua\/en\/wp-json\/wp\/v2\/product_tag?post=9973"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}