Biopsy of the Vater nipple
700 UAH
Biopsy of Vater's nipple (major duodenal papilla) — diagnostic examination of tissues in the area where the bile and pancreatic ducts enter the duodenum, which allows detecting tumor and inflammatory changes in the early stages.
Why is it prescribed: in case of suspected benign or malignant formations (adenomas, carcinomas) of the nipple of Vater, narrowing (stenosis) of the nipple, impaired outflow of bile or pancreatic juice of unknown origin, as well as obstructive mechanical jaundice.
Material for research: biopsy (fragment of the mucosa and tissues of the nipple of Vater, taken during endoscopy / EFGS).
Method: histological / pathomorphological examination.
Biopsy of the Vater nipple — is the taking of a tissue sample from the confluence of the common bile duct and pancreatic duct into the duodenum. This is a technically complex and extremely responsible study performed during endoscopy (EGD or ERCP) for the differential diagnosis between benign changes and tumors in this area.
Research objective: The main task is to determine the cause of the obstruction of bile or pancreatic secretion. Since the papilla of Vater has a complex anatomical structure, pathomorphological analysis is the only way to distinguish inflammatory edema (papilitis) or stenosis from adenoma or cancer (ampullary carcinoma).
What does the pathologist evaluate:
Epithelium type: assessment of changes in the mucous membrane in the ampulla area.
Presence of adenoma: detection of benign growths that have a high potential to degenerate into cancer.
Signs of malignancy: search for atypical cells indicating the development of adenocarcinoma.
Degree of dysplasia: assessment of precancerous changes in nipple tissues.
Inflammatory changes: diagnosis of chronic papillitis, which can cause mechanical jaundice.
Clinical significance: The biopsy results determine the radicality of further treatment. If a benign adenoma is detected, its endoscopic removal (papilectomy) is possible. If a malignant process is confirmed, the patient usually requires a complex surgical operation (pancreatoduodenal resection).
When is it prescribed:
visual thickening, deformation, or enlargement of the nipple of Vater during endoscopy;
mechanical jaundice of unknown origin;
dilation of the bile or pancreatic ducts according to ultrasound, MRI or CT scan;
suspected tumor of the ampullary zone;
control after endoscopic removal of neoplasms of this location.
| Execution time | 2 days |
|---|---|
| Type of biomaterial | Tissues and organs |
Useful tests
