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Neurotransmitters: The Chemistry of Emotion, Memory, and Behavior

illustration of neurons and signal transmission

What are neurotransmitters?

Neurotransmitters are biochemicals that transmit signals between nerve cells (neurons) in the brain and throughout the nervous system. They are also called neurotransmitters. They are the main “messengers” of the nervous system, responsible for mood, anxiety levels, concentration, appetite, sleep, and even pain.

When a neuron receives an electrical impulse, it releases a certain neurotransmitter into the synaptic cleft, the space between cells. Another neuron receives this signal through receptors. This is how everything from thoughts to body movements is formed.

Types of neurotransmitters and their functions

Name of the neurotransmitterMain functionsImbalance manifests itself as
SerotoninMood, appetite, sleep, memoryDepression, anxiety, sleep disorders
DopamineMotivation, pleasure, movement, learningParkinson's, apathy, addiction, psychosis
NoradrenalineFocus, arousal, stress responseAnxiety disorders, hyperactivity
GABAInhibitory effect, anxiety reductionConvulsions, panic attacks, anxiety
GlutamateNeuronal excitation, memory, learningNeurodegeneration, epilepsy
AcetylcholineMuscle activity, attention, memoryAlzheimer's disease, coordination disorders
EndorphinsPain, pleasure, emotional comfortIrritability, decreased pain threshold
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table of neurotransmitters and their functions

Examples of the action of neurotransmitters in everyday life

  • Coffee stimulates the release of dopamine and norepinephrine — that's why we feel a surge of energy after a cup of coffee.

  • Physical exercises increase endorphin levels — this explains the feeling of euphoria after running (“runner's high”).

  • Sweet temporarily stimulates serotonin — that's why we reach for it in stressful situations.

  • Antidepressants work by blocking the reuptake of serotonin or norepinephrine, leaving more of these substances in the synapses.

Why is neurotransmitter balance important?

Neurotransmitters work in close collaboration. For example, an excess of dopamine without the inhibitory action of GABA can cause hyperactivity or mania. A deficiency of acetylcholine is associated with decreased cognitive function.

A study published on Mayo Clinic, confirms that changes in neurotransmitter levels have a significant impact on mental health, although it is only one factor in a complex brain system.

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How can you influence neurotransmitter balance?

  • Healthy sleep: improves serotonin level and dopamine

  • Physical activity: stimulates the release of endorphins and noradrenaline

  • Food: foods rich in tryptophan (meat, eggs, bananas) - a source of serotonin

  • Therapy and meditation: reduce the activity of stress neurotransmitters

  • Medicines: antidepressants, neuroleptics, nootropics, etc.

Neurotransmitters are not just molecules. They are invisible participants in our every thought, reaction, joy, or fear. Their balance is the key to harmonious brain function, mental and physical well-being.

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