Antibodies to desmoglein-3 (Dsg3), IgG
1,700 UAH
Antibodies to desmoglein-3 (Dsg3), IgG — blood test to detect autoantibodies to desmoglein-3, a protein involved in the adhesion of epithelial cells. The study is important in cases of suspected pemphigus, especially pemphigus vulgaris, which is often accompanied by mucosal lesions. The result is evaluated together with clinical manifestations and other studies.
Research on antibodies to desmoglein-3 (Dsg3), IgG used for the diagnosis of autoimmune bullous skin diseases, primarily pemphigus (vulgar form). Desmoglein-3 is a structural protein that ensures the connection of epidermal cells. Production antibodies against it lead to blister formation and erosion.
What does the test show?
Presence of IgG autoantibodies to Dsg3
Autoimmune process activity
Confirmation of the diagnosis of pemphigus
Monitoring the effectiveness of treatment
Who is recommended?
Patients with suspected pemphigus vulgaris
If blisters, erosions of the oral cavity or skin appear
For differentiation from other dermatoses
During immunosuppressant therapy - to monitor the dynamics
What does the result mean?
Positive result: indicates the presence of autoantibodies and supports the diagnosis of pemphigus
Negative result: antibodies are not detected or their level is below the diagnostic threshold
Preparation for analysis
No special preparation is required. The sample is taken from venous blood.
Laboratory Medilab Plus performs research on modern equipment with high accuracy and reliability for the diagnosis of autoimmune dermatological conditions.
| Execution time | 1 day |
|---|---|
| Type of biomaterial | Venous blood |
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