Ferritin
🔬Ferritin is the main indicator of iron stores in the body; it plays an important role in maintaining iron in a biologically useful form.
🔬Ferritin is a complex water-soluble protein complex consisting of 24 identical subunits and capable of attaching about 4,500 iron atoms to one molecule, which is associated with its biological function: the deposition of iron (toxic and non-toxic, physiologically available form for the body).
A fully iron-saturated ferritin molecule contains iron up to 271% of its molecular weight.
Ferritin is synthesized by cells of various tissues, as it is present in all cells and fluids of the body: liver, spleen, bone marrow, heart muscle, lungs, kidneys, thyroid gland, placenta, small intestine, pancreas.
⬆️Elevated ferritin levels may indicate an acute or chronic inflammatory process that interferes with oxygen transport and disrupts red blood cell function.
⬇️A low level of ferritin indicates chronic iron deficiency - anemia.
❗️In COVID-19, caused by coronavirus infection, oxygen transport is impaired, which in turn affects the course of the disease. Increased ferritin levels play a significant role in the severity of the disease.
📍Extremely high levels of ferritin contribute to the development of respiratory failure - acute respiratory distress syndrome (ARDS), in which the patient may be prescribed a ventilator (MVL).
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Head of the clinical diagnostic laboratory of Medi Lab Plus LLC, Master of Biochemistry with over 15 years of management experience. Monitors compliance of research with international EUCAST protocols and ISO 15189 standard. Acts as a medical editor of the site materials. More details…