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Autoimmune diseases are a group of pathologies in which the body's immune system attacks its own cells and tissues. This can occur through the production of antibodies to its own proteins or other components of the body. One of the methods for diagnosing and monitoring autoimmune diseases is to determine the level of antibodies to certain antigens. The hepato/nephrology panel, composed of 10 antigens, plays an important role in the detection and monitoring of these diseases.

Autoimmune hepatitis: Autoimmune hepatitis is a liver disease in which the immune system produces antibodies against liver cells. Detection of antibodies to antigens such as ANA (antinuclear antibodies) and SMA (antimicrosomal antibodies) helps in early detection and management of this disease.
IgA deposition nephropathy: Immunoglobulin A (IgA) nephropathy is a kidney disease in which IgA is deposited in the kidneys, causing inflammation. Measuring the level of antibodies to IgA can be useful in diagnosing and monitoring this disease.
Celiac disease: Celiac disease is an autoimmune disease in which exposure to gluten causes damage to the small intestine. Celiac disease is diagnosed by detecting antibodies to antigens such as anti-tTG (anti-transglutaminase antibodies).
Systemic lupus erythematosus: Antinuclear antibodies (ANA) and antibodies to double-stranded DNA (dsDNA) help detect systemic lupus erythematosus, which can affect not only the kidneys but also other organs.
Scleroderma: In the case of systemic scleroderma, the determination of antibodies to Scl-70 or anti-centromere antibodies is important for early diagnosis and monitoring of the disease.
Grave's disease: Graves' is an autoimmune disease of the thyroid gland. The determination of antibodies to TPO (thyroperoxidase) and TG (thyroglobulin) helps in the diagnosis and monitoring of this disease.
Systemic lupus erythematosus: For systemic lupus, ANA and dsDNA are important antibodies. They help establish the diagnosis and assess the activity of the disease.
Rheumatoid arthritis: Rheumatoid factor (RF) and antibodies to cyclic citrullinated peptide (anti-CCP) help in the diagnosis of rheumatoid arthritis.
Sjögren's syndrome: The diagnosis of Sjögren's syndrome is confirmed by the determination of antibodies to SSA (Ro) and SSB (La).
Myositis: Antibodies to Jo-1 and other anti-tRNA antibodies may indicate the presence of myositis, an autoimmune disease of the muscles.

The hepato/nephrology panel with these 10 antigens allows doctors to accurately diagnose autoimmune diseases and monitor the effectiveness of treatment. It is important to note that antibody levels can fluctuate over time, so regular monitoring is key to managing the disease and maintaining the patient's condition at an optimal level.

May the hepato/nephrology panel in autoimmunology serve as a tool for early diagnosis and effective control of autoimmune diseases, contributing to improving the quality of life of affected patients.

Hepato/nephrology panel (10 antigens)

1,100 UAH

Autoimmunology/

Indicators:

AMA M2 (primary biliary cirrhosis);
Sp 100 (primary biliary cirrhosis);
gp 210 (primary biliary cirrhosis of the liver);
LKM 1 (autoimmune hepatitis type II);
LC 1 (autoimmune hepatitis type II));
CENP-B (subacute SLE, CREST syndrome, Raynaud's phenomenon, primary biliary cirrhosis);
GBM (Goodpasture's syndrome);
PR3 (ANTSA vasculitis, Wegener's granulomatosis);
MPO (ANTSA vasculitis, Churg-Strauss syndrome, microscopic polyangiitis);
SLA/LP (autoimmune hepatitis type III).