Interleukin-6

📍 IL-6 is an anti-inflammatory cytokine that affects the body as a whole, increases inflammatory processes and contributes to the exacerbation of chronic diseases of the cardiovascular and respiratory systems, and also disrupts the functioning of the liver, immune and endocrine systems, and metabolism. It is a marker of acute systemic inflammation.
🚨 IL-6 is synthesized:
– activated monocytes/macrophages;
– fibroblasts;
– endothelial cells in inflammation, trauma, hypoxia, bacterial infections.
The anti-inflammatory cytokine IL-6 is produced rapidly and is increased during acute inflammatory responses associated with injury, trauma, stress, infection, and other pathological conditions. IL-6 concentrations in trauma patients may serve as precursors of late complications of surgical treatment or as a marker of undiagnosed injuries or complications. Serial measurements of interleukin-6 in serum or plasma of patients admitted to the intensive care unit and resuscitation. have been successfully used to assess the severity of SIRS (systemic inflammatory response syndrome), sepsis, and septic shock, as well as to predict clinical outcome in such patients.
❗️Depending on the results of this IL-6 study, a decision is made on further treatment of a patient with coronavirus (COVID-19).