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Serotonin levels: why the «happiness hormone» is important for the whole body

Serotonin molecule on the background of the brain
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What is serotonin and what role does it play?

Serotonin is a chemical that acts as a neurotransmitter in the brain and how hormone in the blood. It is often called the "happiness hormone", but in fact it is responsible not only for a good mood, but also for a number of vital functions:

  • mood and anxiety regulation

  • appetite and sleep control

  • gastrointestinal tract function

  • vasoconstriction and pain regulation

  • sexual behavior and emotional stability

Close 90% serotonin is not produced in the brain, but in intestines, particularly in enterochromaffin-type cells.

Symptoms of low serotonin levels

Serotonin deficiency can manifest itself in different ways, depending on the body. The most common signs are:

  • chronic fatigue

  • depressed mood, apathy

  • anxiety, excessive excitement

  • sleep disturbance (insomnia, frequent awakenings)

  • decreased libido

  • increased cravings for sweets or carbohydrates

  • irritability, emotional instability

  • headaches or migraines

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What factors affect serotonin levels?

FactorInfluence
Chronic stressReduces serotonin synthesis through enzyme inhibition
Deficiency of the amino acid tryptophanThe main raw material for the formation of serotonin
Sleep deprivationDisrupts circadian rhythms and neurotransmitter synthesis
Lack of sunlightLow vitamin D slows down serotonin production
Gastrointestinal diseasesTryptophan absorption and microbiota regulation are impaired
Some medicationsSome antidepressants increase, while hormonal drugs decrease, serotonin levels.

How to measure serotonin levels

To assess serotonin levels, it is used blood test or urine, although the accuracy of such methods limited, because the serotonin content in peripheral tissues does not always correspond to the brain level.

Serotonin is most often tested for:

  • upon suspicion of serotonin syndrome (drug overdose)

  • in diagnostics neuroendocrine tumors (carcinoid)

  • at complex psychiatric disorders

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Alternatively, doctors assess serotonin levels indirectly, due to symptoms, response to therapy, and tests for tryptophan, B vitamins, vitamin D, microbiota.

man in the sun with a smile

How to naturally increase serotonin levels

  • Regular physical activity — even a 20-minute walk every day

  • Sunlight — 15–30 minutes a day

  • Foods high in tryptophan:

    • bananas

    • salmon

    • eggs

    • nuts

    • fermented milk products

  • Prebiotics and probiotics to maintain microbiota

  • Relaxation techniques — meditation, yoga, breathing exercises

  • Social contacts — communication, hugs, support

Practical example

The patient complains of depressed mood, cravings for sweets, and insomnia. Urine analysis shows a reduced level of serotonin metabolites. After correcting the diet, adding daily walks, and prescribing adaptogens, the condition improves after 3 weeks.

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Serotonin is not only about emotions, but also about the overall functioning of the body. The level of this substance depends not only on genetics, but also on our lifestyle. And it is on it that how we feel every day largely depends.

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